Basics to Brilliance: Haematology Podcast
Welcome to Basics to Brilliance, the podcast created to supplement & bolster your knowledge of Haematology.
Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are.
We aim to cover:
- Malignant and non-malignant topics
- Science/lab detail
- UK guidelines, hallmark trials and how these translate into clinical practice
- Future research directions
- The whole syllabus for FRCPath part 1
All readily accessible and completely free of charge!
For every budding haematologist out there, we hope this podcast aids you in your endeavours and fills you with interest and excitement for the brilliant world of Haematology.
Warmest Regards,
Dr. Everden
Dr. Fasey
Dr. Jafri
Disclaimer: This podcast is intended as a revision aid and should not be used for the medical management of patients. Guidelines in the initial episodes span 2023/2024. We aim to update our content in accordance with the most recent available guidelines when possible.
This podcast is CPD accredited by the Royal College of Pathologists UK
Basics to Brilliance: Haematology Podcast
Factor XIII (13), Fibrinolysis & Thrombolysis
01:45 Case: Neonate with repeated umblical bleeding. IC haemorrhage. Normal Factors (so far), Normal VW screen, Normal FBC and normal film.
05:35 Factor XIII (13): function and presentations in deficiency
09:45 Testing, testing!
- ELISA/Ammonia Release Assay then a Mutational Analysis
- Honarable mention: Clot Solubility Assay
16:00 Fibrinolysis definition and pathway
21:00 Activators of Fibrinolysis: tPA vs. uPA
23:23 Inhibitors of Fibrinolysis: PAI-1, PAI-2, TAFI, α2-antiplasmin, and Factor XIII (13)
26:28 Thrombolysis: defintion, examples and uses
32:20 Case: Thromboembolic stroke, thrombolysis 24 hours prior, haemorrhagic transformation
36:19: Tranexamic Acid (Hari’s favourite drug)
- Honarable mention: Dr Utako Okamoto and the WOMAN trial
- CRASH 2 and CRASH 3 trials
- HALT-IT trial
41:22 D-Dimer
44:00 Summary
'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK.
Medical professionals and clinical scientists holding career-grade positions, who are registered with any of the Royal Colleges for CPD, will be eligible to earn 1 credit for every hour of learning.
Email: basicstobrilliancehaem@gmail.com
Insta: BasicstoBrilliance
X: @basics_2_brill
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